6XXN
Crystal structure of NB7, a nanobody targeting prostate specific membrane antigen
Summary for 6XXN
Entry DOI | 10.2210/pdb6xxn/pdb |
Descriptor | NB_7_a,b,c,f, NB_7_g, NB_7_h, ... (5 entities in total) |
Functional Keywords | nanobody, prostate specific membrane, antigen, antibody drug conjugate, cancer imaging, anti-cancer drugs, antitumor protein |
Biological source | Camelus dromedarius (Arabian camel) More |
Total number of polymer chains | 8 |
Total formula weight | 130538.01 |
Authors | Shahar, A.,Rosenfeld, L.,Papo, N. (deposition date: 2020-01-28, release date: 2020-06-10, Last modification date: 2024-01-24) |
Primary citation | Rosenfeld, L.,Sananes, A.,Zur, Y.,Cohen, S.,Dhara, K.,Gelkop, S.,Ben Zeev, E.,Shahar, A.,Lobel, L.,Akabayov, B.,Arbely, E.,Papo, N. Nanobodies Targeting Prostate-Specific Membrane Antigen for the Imaging and Therapy of Prostate Cancer. J.Med.Chem., 63:7601-7615, 2020 Cited by PubMed: 32442375DOI: 10.1021/acs.jmedchem.0c00418 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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