6XXN

Crystal structure of NB7, a nanobody targeting prostate specific membrane antigen

Summary for 6XXN

• Entry DOI: 10.2210/pdb6xxn/pdb
• Descriptor: NB_7_a,b,c,f, NB_7_g, NB_7_h, ... (5 entities in total)
• Functional Keywords: nanobody, prostate specific membrane, antigen, antibody drug conjugate, cancer imaging, anti-cancer drugs, antitumor protein
• Biological source: Camelus dromedarius (Arabian camel); More
• Total number of polymer chains: 8
• Total formula weight: 130538.01

Authors

Shahar, A.,Rosenfeld, L.,Papo, N. (deposition date: 2020-01-28, release date: 2020-06-10, Last modification date: 2024-01-24)

• Primary citation: Rosenfeld, L.,Sananes, A.,Zur, Y.,Cohen, S.,Dhara, K.,Gelkop, S.,Ben Zeev, E.,Shahar, A.,Lobel, L.,Akabayov, B.,Arbely, E.,Papo, N.; Nanobodies Targeting Prostate-Specific Membrane Antigen for the Imaging and Therapy of Prostate Cancer.; J.Med.Chem., 63:7601-7615, 2020; PubMed: 32442375; DOI: 10.1021/acs.jmedchem.0c00418

Experimental method

X-RAY DIFFRACTION (2.65 Å)