6XX0

Crystal structure of NEMO in complex with Ubv-LIN

6XX0 の概要

• エントリーDOI: 10.2210/pdb6xx0/pdb
• 分子名称: Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b, Ubv-LIN (3 entities in total)
• 機能のキーワード: inhibitor, ubiquitin, protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 38561.92

構造登録者

Akutsu, M.,Skenderovic, A.,Garcia-Pardo, J.,Maculins, T.,Dikic, I. (登録日: 2020-01-26, 公開日: 2021-02-03, 最終更新日: 2024-01-24)

• 主引用文献: Maculins, T.,Garcia-Pardo, J.,Skenderovic, A.,Gebel, J.,Putyrski, M.,Vorobyov, A.,Busse, P.,Varga, G.,Kuzikov, M.,Zaliani, A.,Rahighi, S.,Schaeffer, V.,Parnham, M.J.,Sidhu, S.S.,Ernst, A.,Dotsch, V.,Akutsu, M.,Dikic, I.; Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms.; Cell Chem Biol, 27:1441-1451.e7, 2020; PubMed: 32726587; DOI: 10.1016/j.chembiol.2020.07.010

実験手法

X-RAY DIFFRACTION (2.6 Å)