6XVD

Crystal structure of complex of urokinase and a upain-1 variant(W3F) in pH7.4 condition

6XVD の概要

• エントリーDOI: 10.2210/pdb6xvd/pdb
• 分子名称: Urokinase-type plasminogen activator, upain-1-W3F (3 entities in total)
• 機能のキーワード: upain-1-w3f, urokinase, cyclic peptide inhibitor, peptide binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29811.97

構造登録者

Xue, G.P.,Xie, X.,Zhou, Y.,Yuan, C.,Huang, M.D.,Jiang, L.G. (登録日: 2020-01-21, 公開日: 2020-02-19, 最終更新日: 2024-01-24)

• 主引用文献: Xue, G.,Xie, X.,Zhou, Y.,Yuan, C.,Huang, M.,Jiang, L.; Insight to the residue in P2 position prevents the peptide inhibitor from being hydrolyzed by serine proteases.; Biosci.Biotechnol.Biochem., 84:1153-1159, 2020; PubMed: 32019421; DOI: 10.1080/09168451.2020.1723405

実験手法

X-RAY DIFFRACTION (1.4 Å)