6XTA
Recombinant human butyrylcholinesterase in complex with (2S)-N-[2-(1-benzylazepan-4-yl)ethyl]-2-(butylamino)-3-(1H-indol-3-yl)propanamide
Summary for 6XTA
Entry DOI | 10.2210/pdb6xta/pdb |
Descriptor | Cholinesterase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | butyrylcholinesterase, inhibitor, complex, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 62587.83 |
Authors | Brazzolotto, X.,Nachon, F.,Meden, A.,Knez, D.,Gobec, S. (deposition date: 2020-01-15, release date: 2020-10-28, Last modification date: 2024-01-24) |
Primary citation | Meden, A.,Knez, D.,Malikowska-Racia, N.,Brazzolotto, X.,Nachon, F.,Svete, J.,Salat, K.,Groselj, U.,Gobec, S. Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors. Eur.J.Med.Chem., 208:112766-112766, 2020 Cited by PubMed: 32919297DOI: 10.1016/j.ejmech.2020.112766 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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