6XRO

Crystal structure of GlpG in complex with peptide boronate inhibitor, Ac-KRFRSMQYSA-B(OH)2

6XRO の概要

• エントリーDOI: 10.2210/pdb6xro/pdb
• 分子名称: Rhomboid protease GlpG, peptide boronate inhibitor, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: glpg, rhomboid protease, hydrolase-hydrolase inhibitor complex, membrane protein, hydrolase/hydrolase inhibitor
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 25209.31

構造登録者

Urban, S.,Cho, S. (登録日: 2020-07-13, 公開日: 2020-09-16, 最終更新日: 2024-04-24)

• 主引用文献: Gandhi, S.,Baker, R.P.,Cho, S.,Stanchev, S.,Strisovsky, K.,Urban, S.; Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria.; Cell Chem Biol, 27:1410-1424.e6, 2020; PubMed: 32888502; DOI: 10.1016/j.chembiol.2020.08.011

実験手法

X-RAY DIFFRACTION (2.3 Å)