6XQ6

Receptor for Advanced Glycation End Products VC1 domain in complex with Fragment 11

Summary for 6XQ6

Entry DOI	10.2210/pdb6xq6/pdb
Related	6XQ1 6XQ3 6XQ5
Descriptor	Advanced glycosylation end product-specific receptor, ACETATE ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	rage, ig-like domain, receptor, advanced glycation end products, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	47305.82
Authors	Salay, L.E.,Kozlyuk, N.,Gilston, B.A.,Gogliotti, R.D.,Christov, P.P.,Kim, K.,Ovee, M.,Waterson, A.G.,Chazin, W.J. (deposition date: 2020-07-09, release date: 2021-07-14, Last modification date: 2023-10-18)
Primary citation	Kozlyuk, N.,Gilston, B.A.,Salay, L.E.,Gogliotti, R.D.,Christov, P.P.,Kim, K.,Ovee, M.,Waterson, A.G.,Chazin, W.J. A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors. Proteins, 89:1399-1412, 2021 Cited by PubMed: 34156100 DOI: 10.1002/prot.26162 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation