6XQ1

Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-((4-(4-carboxyphenoxy)benzyl)oxy)phenyl)-1H-indole-2-carboxylic acid

6XQ1 の概要

• エントリーDOI: 10.2210/pdb6xq1/pdb
• 分子名称: Advanced glycosylation end product-specific receptor, ACETATE ION, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: rage, inhibitor, receptor, advanced glycation end products, signaling protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47734.22

構造登録者

Salay, L.E.,Kozlyuk, N.,Gilston, B.A.,Gogliotti, R.D.,Christov, P.P.,Kim, K.,Ovee, M.,Waterson, A.G.,Chazin, W.J. (登録日: 2020-07-09, 公開日: 2021-07-14, 最終更新日: 2023-10-18)

• 主引用文献: Kozlyuk, N.,Gilston, B.A.,Salay, L.E.,Gogliotti, R.D.,Christov, P.P.,Kim, K.,Ovee, M.,Waterson, A.G.,Chazin, W.J.; A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.; Proteins, 89:1399-1412, 2021; PubMed: 34156100; DOI: 10.1002/prot.26162

実験手法

X-RAY DIFFRACTION (1.51 Å)