6XPC
Structure of human GGT1 in complex with full GSH molecule
Summary for 6XPC
| Entry DOI | 10.2210/pdb6xpc/pdb |
| Descriptor | Glutathione hydrolase 1 heavy chain, Glutathione hydrolase 1 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
| Functional Keywords | substrate-enzyme complex, ntn-hydrolase family, glycoprotein, n-glycosylation, cell surface, hydrolase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 60276.57 |
| Authors | Terzyan, S.S.,Hanigan, M. (deposition date: 2020-07-08, release date: 2020-11-25, Last modification date: 2023-10-18) |
| Primary citation | Terzyan, S.S.,Nguyen, L.T.,Burgett, A.W.G.,Heroux, A.,Smith, C.A.,You, Y.,Hanigan, M.H. Crystal structures of glutathione- and inhibitor-bound human GGT1: critical interactions within the cysteinylglycine binding site. J.Biol.Chem., 296:100066-100066, 2020 Cited by PubMed: 33187988DOI: 10.1074/jbc.RA120.016265 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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