6XLG

Full-length Hsc82 in complex with two Aha1 CTD in the presence of ATPgammaS

Summary for 6XLG

• Entry DOI: 10.2210/pdb6xlg/pdb
• EMDB information: 22243
• Descriptor: ATP-dependent molecular chaperone HSC82, Hsp90 co-chaperone AHA1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... (5 entities in total)
• Functional Keywords: co-chaperone, activator, chaperone
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 4
• Total formula weight: 242153.33

Authors

Liu, Y.X.,Sun, M.,Myasnikov, A.G.,Elnatan, D.,Agard, D.A. (deposition date: 2020-06-28, release date: 2021-06-30, Last modification date: 2024-03-06)

• Primary citation: Liu, Y.X.,Sun, M.,Myasnikov, A.G.,Elnatan, D.,Agard, D.A.; Cryo-EM structures reveal a multistep mechanism of Hsp90 activation by co-chaperone Aha1; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.71 Å)