6XLF

Full-length Hsc82 in complex with Aha1 in the presence of AMP-PNP

Summary for 6XLF

• Entry DOI: 10.2210/pdb6xlf/pdb
• EMDB information: 22242
• Descriptor: ATP-dependent molecular chaperone HSC82, Hsp90 co-chaperone AHA1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
• Functional Keywords: co-chaperone, activator, chaperone
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 4
• Total formula weight: 242119.23

Authors

Liu, Y.X.,Sun, M.,Myasnikov, A.G.,Elnatan, D.,Agard, D.A. (deposition date: 2020-06-28, release date: 2021-06-30)

• Primary citation: Liu, Y.X.,Sun, M.,Myasnikov, A.G.,Elnatan, D.,Agard, D.A.; Cryo-EM structures reveal a multistep mechanism of Hsp90 activation by co-chaperone Aha1; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.15 Å)