6XL1

crystal structure of cA4-activated Card1(D294N)

Summary for 6XL1

• Entry DOI: 10.2210/pdb6xl1/pdb
• Descriptor: Card1, cA4, MANGANESE (II) ION, ... (5 entities in total)
• Functional Keywords: cad1, dnase, cyclic oligoadenylates, dna binding protein, dna binding protein-rna complex, dna binding protein/rna
• Biological source: Treponema succinifaciens DSM 2489; More
• Total number of polymer chains: 3
• Total formula weight: 91754.04

Authors

Rostol, J.,Xie, W.,Patel, D.J.,Marraffini, L. (deposition date: 2020-06-27, release date: 2020-12-30, Last modification date: 2023-10-18)

• Primary citation: Rostol, J.T.,Xie, W.,Kuryavyi, V.,Maguin, P.,Kao, K.,Froom, R.,Patel, D.J.,Marraffini, L.A.; The Card1 nuclease provides defence during type III CRISPR immunity.; Nature, 590:624-629, 2021; PubMed: 33461211; DOI: 10.1038/s41586-021-03206-x

Experimental method

X-RAY DIFFRACTION (1.95 Å)