6XJQ
Crystal structure of a self-alkylating ribozyme - alkylated form with biotinylated epoxide substrate
Summary for 6XJQ
Entry DOI | 10.2210/pdb6xjq/pdb |
Descriptor | Self-alkylating ribozyme (58-MER), Fab HAVx Heavy Chain, Fab HAVx Light Chain, ... (5 entities in total) |
Functional Keywords | self-alkylating ribozyme, antibody-assisted rna crystallography, rna catalysis, rna-immune system complex, rna/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 146004.44 |
Authors | Koirala, D.,Piccirilli, J.A. (deposition date: 2020-06-24, release date: 2022-01-19, Last modification date: 2023-10-18) |
Primary citation | Krochmal, D.,Shao, Y.,Li, N.S.,DasGupta, S.,Shelke, S.A.,Koirala, D.,Piccirilli, J.A. Structural basis for substrate binding and catalysis by a self-alkylating ribozyme. Nat.Chem.Biol., 18:376-384, 2022 Cited by PubMed: 35058645DOI: 10.1038/s41589-021-00950-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.708 Å) |
Structure validation
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