6XEZ
Structure of SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC
Summary for 6XEZ
Entry DOI | 10.2210/pdb6xez/pdb |
EMDB information | 22160 22270 22271 |
Descriptor | RNA-directed RNA polymerase, CHAPSO, ALUMINUM FLUORIDE, ... (11 entities in total) |
Functional Keywords | rna-dependent rna polymerase, viral replication-transcription complex, transcription, viral proteins, transferase-hydrolase-rna complex, transferase/hydrolase/rna |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 8 |
Total formula weight | 327962.35 |
Authors | Chen, J.,Malone, B.,Llewellyn, E.C.,Campbell, E.A.,Darst, S.A. (deposition date: 2020-06-14, release date: 2020-07-29, Last modification date: 2024-03-06) |
Primary citation | Chen, J.,Malone, B.,Llewellyn, E.,Grasso, M.,Shelton, P.M.M.,Olinares, P.D.B.,Maruthi, K.,Eng, E.T.,Vatandaslar, H.,Chait, B.T.,Kapoor, T.M.,Darst, S.A.,Campbell, E.A. Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex. Cell, 182:1560-1573.e13, 2020 Cited by PubMed: 32783916DOI: 10.1016/j.cell.2020.07.033 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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