6XDS

Crystal structure of MBP-TREM2 Ig domain fusion with fragment, 2-((4-bromophenyl)amino)ethan-1-ol

Summary for 6XDS

Entry DOI	10.2210/pdb6xds/pdb
Related PRD ID	PRD_900009
Descriptor	Sugar ABC transporter substrate-binding protein,Triggering receptor expressed on myeloid cells 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 2-[(4-bromophenyl)amino]ethan-1-ol, ... (5 entities in total)
Functional Keywords	trem2, mbp, crystallization, chaperone, signaling protein
Biological source	Methanosarcina mazei More
Total number of polymer chains	1
Total formula weight	55126.98
Authors	Su, H.P. (deposition date: 2020-06-11, release date: 2021-02-17)
Primary citation	Byrne, N.J.,Lee, A.C.,Kostas, J.,Reid, J.C.,Partridge, A.T.,So, S.S.,Cowan, J.E.,Abeywickrema, P.,Huang, H.,Zebisch, M.,Barker, J.J.,Soisson, S.M.,Brooun, A.,Su, H.P. Development of a robust crystallization platform for immune receptor TREM2 using a crystallization chaperone strategy. Protein Expr.Purif., 179:105796-105796, 2021 Cited by PubMed: 33221505 DOI: 10.1016/j.pep.2020.105796 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.466 Å)

Structure validation