6XDS

Crystal structure of MBP-TREM2 Ig domain fusion with fragment, 2-((4-bromophenyl)amino)ethan-1-ol

6XDS の概要

• エントリーDOI: 10.2210/pdb6xds/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900009
• 分子名称: Sugar ABC transporter substrate-binding protein,Triggering receptor expressed on myeloid cells 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 2-[(4-bromophenyl)amino]ethan-1-ol, ... (5 entities in total)
• 機能のキーワード: trem2, mbp, crystallization, chaperone, signaling protein
• 由来する生物種: Methanosarcina mazei; 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 55126.98

構造登録者

Su, H.P. (登録日: 2020-06-11, 公開日: 2021-02-17)

• 主引用文献: Byrne, N.J.,Lee, A.C.,Kostas, J.,Reid, J.C.,Partridge, A.T.,So, S.S.,Cowan, J.E.,Abeywickrema, P.,Huang, H.,Zebisch, M.,Barker, J.J.,Soisson, S.M.,Brooun, A.,Su, H.P.; Development of a robust crystallization platform for immune receptor TREM2 using a crystallization chaperone strategy.; Protein Expr.Purif., 179:105796-105796, 2021; PubMed: 33221505; DOI: 10.1016/j.pep.2020.105796

実験手法

X-RAY DIFFRACTION (1.466 Å)