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6XD5

Apo KPC-2 N170A mutant at 1.20 A

Summary for 6XD5
Entry DOI10.2210/pdb6xd5/pdb
DescriptorCarbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL, SULFATE ION, ... (4 entities in total)
Functional Keywordscarbapenemase, beta-lactamase, hydrolase
Biological sourceKlebsiella pneumoniae
Total number of polymer chains1
Total formula weight31577.57
Authors
Pemberton, O.A.,Chen, Y. (deposition date: 2020-06-10, release date: 2020-12-09, Last modification date: 2023-10-18)
Primary citationMehta, S.C.,Furey, I.M.,Pemberton, O.A.,Boragine, D.M.,Chen, Y.,Palzkill, T.
KPC-2 beta-lactamase enables carbapenem antibiotic resistance through fast deacylation of the covalent intermediate.
J.Biol.Chem., 296:100155-100155, 2020
Cited by
PubMed: 33273017
DOI: 10.1074/jbc.RA120.015050
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.2 Å)
Structure validation

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