6XCM
Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 1)
Summary for 6XCM
Entry DOI | 10.2210/pdb6xcm/pdb |
EMDB information | 22127 22128 |
Descriptor | Spike glycoprotein, C105 Fab Heavy Chain, C105 Fab Light Chain, ... (8 entities in total) |
Functional Keywords | sars-cov-2, spike glycoprotein, covid-19, monoclonal neutralizing antibody, fabs, nsempem, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 7 |
Total formula weight | 527029.15 |
Authors | Barnes, C.O.,Bjorkman, P.J. (deposition date: 2020-06-08, release date: 2020-07-01, Last modification date: 2020-09-02) |
Primary citation | Barnes, C.O.,West Jr., A.P.,Huey-Tubman, K.E.,Hoffmann, M.A.G.,Sharaf, N.G.,Hoffman, P.R.,Koranda, N.,Gristick, H.B.,Gaebler, C.,Muecksch, F.,Lorenzi, J.C.C.,Finkin, S.,Hagglof, T.,Hurley, A.,Millard, K.G.,Weisblum, Y.,Schmidt, F.,Hatziioannou, T.,Bieniasz, P.D.,Caskey, M.,Robbiani, D.F.,Nussenzweig, M.C.,Bjorkman, P.J. Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies. Cell, 182:828-, 2020 Cited by PubMed: 32645326DOI: 10.1016/j.cell.2020.06.025 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.42 Å) |
Structure validation
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