6XCL
Crystal Structure of human telomeric DNA G-quadruplex in complex with a novel platinum(II) complex.
Summary for 6XCL
Entry DOI | 10.2210/pdb6xcl/pdb |
Descriptor | DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Platinum(II) bis[3-(pyridin-2-yl)-[1,2,4]triazolo[4,3-a]pyridine], 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | guanine quadruplex, ligand complex, dna |
Biological source | Homo sapiens |
Total number of polymer chains | 2 |
Total formula weight | 16049.10 |
Authors | Miron, C.E.,van Staalduinen, L.M.,Jia, Z.,Petitjean, A. (deposition date: 2020-06-08, release date: 2020-11-04, Last modification date: 2023-10-18) |
Primary citation | Miron, C.E.,van Staalduinen, L.,Rangaswamy, A.M.,Chen, M.,Liang, Y.,Jia, Z.,Mergny, J.L.,Petitjean, A. Going Platinum to the Tune of a Remarkable Guanine Quadruplex Binder: Solution- and Solid-State Investigations. Angew.Chem.Int.Ed.Engl., 60:2500-2507, 2021 Cited by PubMed: 33090592DOI: 10.1002/anie.202012520 PDB entries with the same primary citation |
Experimental method |
Structure validation
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