6XCH

Room-temperature X-ray Crystal structure of SARS-CoV-2 main protease in complex with Leupeptin

Summary for 6XCH

Entry DOI	10.2210/pdb6xch/pdb
Descriptor	3C-like proteinase, Leupeptin (3 entities in total)
Functional Keywords	sars-cov-2 main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More
Total number of polymer chains	2
Total formula weight	34255.13
Authors	Kneller, D.W.,Kovalevsky, A.,Coates, L. (deposition date: 2020-06-08, release date: 2020-06-17, Last modification date: 2023-10-18)
Primary citation	Kneller, D.W.,Galanie, S.,Phillips, G.,O'Neill, H.M.,Coates, L.,Kovalevsky, A. Malleability of the SARS-CoV-2 3CL M pro Active-Site Cavity Facilitates Binding of Clinical Antivirals. Structure, 28:1313-, 2020 Cited by PubMed: 33152262 DOI: 10.1016/j.str.2020.10.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation