6X5A
The mouse cGAS catalytic domain binding to human nucleosome that purified from HEK293T cells
Summary for 6X5A
Entry DOI | 10.2210/pdb6x5a/pdb |
EMDB information | 22047 |
Descriptor | Histone H3.2, Histone H4, Histone H2A type 1, ... (8 entities in total) |
Functional Keywords | immunity, dna binding protein-dna-transferase complex, dna binding protein/dna/transferase |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 11 |
Total formula weight | 242903.19 |
Authors | Pengbiao, X.,Pingwei, L.,Baoyu, Z. (deposition date: 2020-05-25, release date: 2020-09-16, Last modification date: 2024-03-06) |
Primary citation | Zhao, B.,Xu, P.,Rowlett, C.M.,Jing, T.,Shinde, O.,Lei, Y.,West, A.P.,Liu, W.R.,Li, P. The molecular basis of tight nuclear tethering and inactivation of cGAS. Nature, 587:673-677, 2020 Cited by PubMed: 32911481DOI: 10.1038/s41586-020-2749-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.36 Å) |
Structure validation
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