6X1G

Crystal structure of a GEF domain from the Orientia tsutsugamushi protein OtDUB in complex with Rac1

6X1G の概要

• エントリーDOI: 10.2210/pdb6x1g/pdb
• 分子名称: ULP_PROTEASE domain-containing protein, Ras-related C3 botulinum toxin substrate 1, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: guanine nucleotide exchange factor, gef, rac1, gtpase, orientia tsutsugamushi, scrub typhus, signaling protein, signaling protein-hydrolase complex, signaling protein/hydrolase
• 由来する生物種: Orientia tsutsugamushi (Rickettsia tsutsugamushi); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 91484.66

構造登録者

Lim, C.S.,Xiong, Y. (登録日: 2020-05-18, 公開日: 2020-11-25, 最終更新日: 2023-10-18)

• 主引用文献: Lim, C.,Berk, J.M.,Blaise, A.,Bircher, J.,Koleske, A.J.,Hochstrasser, M.,Xiong, Y.; Crystal structure of a guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi .; Proc.Natl.Acad.Sci.USA, 117:30380-30390, 2020; PubMed: 33184172; DOI: 10.1073/pnas.2018163117

実験手法

X-RAY DIFFRACTION (1.6 Å)