6WYK
Cryo-EM structure of the GltPh L152C-G321C mutant in the intermediate chloride conducting state.
Summary for 6WYK
Entry DOI | 10.2210/pdb6wyk/pdb |
EMDB information | 21967 |
Descriptor | Glutamate transporter homolog, ASPARTIC ACID (2 entities in total) |
Functional Keywords | glutamate transporter homolog gltph, transport protein |
Biological source | Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) |
Total number of polymer chains | 1 |
Total formula weight | 44718.14 |
Authors | Font, J.,Chen, I.,Sobti, M.,Stewart, A.G.,Ryan, R.M. (deposition date: 2020-05-13, release date: 2021-02-17, Last modification date: 2024-03-06) |
Primary citation | Chen, I.,Pant, S.,Wu, Q.,Cater, R.J.,Sobti, M.,Vandenberg, R.J.,Stewart, A.G.,Tajkhorshid, E.,Font, J.,Ryan, R.M. Glutamate transporters have a chloride channel with two hydrophobic gates. Nature, 591:327-331, 2021 Cited by PubMed: 33597752DOI: 10.1038/s41586-021-03240-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
Download full validation report