6WXA

Crystal structure of truncated Streptococcal bacteriophage hyaluronidase complexed with unsaturated hyaluronan hexa-saccharides

Summary for 6WXA

• Entry DOI: 10.2210/pdb6wxa/pdb
• Related: 6WV2
• Descriptor: Hyaluronan lyase, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: hylp, lyase, hyaluronidase, s. pyogenes phage h4489a, beta-elimination, unsaturated hyaluronan hexa-saccharides
• Biological source: Streptococcus pyogenes phage H4489A
• Total number of polymer chains: 3
• Total formula weight: 99429.05

Authors

Deivanayagam, C.,Schormann, N. (deposition date: 2020-05-10, release date: 2021-05-12, Last modification date: 2023-10-18)

• Primary citation: Lee, J.H.,Schormann, N.,Rajashankar, K.R.,Deivanaygam, C.; Crystal Structure of Streptococcal Bacteriophage Hyaluronidase: Presence of a Prokaryotic Collagen and Elucidation of Catalytic Mechanism; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)