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6WX3

High resolution Tryptophan Synthase crystal structure from Salmonella typhimurium in complex with F9 inhibitor in the alpha-site, Cesium ion at the metal coordination site and internal aldimine form.

Summary for 6WX3
Entry DOI10.2210/pdb6wx3/pdb
Related4HT3 4XUG
DescriptorTryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (10 entities in total)
Functional Keywordslyase-inhibitor, protein complex, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological sourceSalmonella typhimurium (Salmonella enterica subsp. enterica serovar Typhimurium)
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Total number of polymer chains2
Total formula weight73386.26
Authors
Hilario, E.,Dunn, M.F.,Mueller, L.J.,Fan, L. (deposition date: 2020-05-09, release date: 2021-03-10, Last modification date: 2023-10-18)
Primary citationHilario, E.,Fan, L.,Dunn, M.F.,Mueller, L.J.
High resolution Tryptophan Synthase crystal structure from Salmonella typhimurium in complex with F9 inhibitor in the alpha-site, Cesium ion at the metal coordination site and internal aldimine form.
To be Published,
Experimental method
X-RAY DIFFRACTION (1.2 Å)
Structure validation

218500

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