6WUI

Crystal Structure of mutant S. pombe Rai1 (E150S/E199Q/E239Q) in complex with 3'-FADP

6WUI の概要

• エントリーDOI: 10.2210/pdb6wui/pdb
• 分子名称: Decapping nuclease din1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) (3 entities in total)
• 機能のキーワード: fad, 3'-fadp, rna, cap, decapping, hydrolase, rai1
• 由来する生物種: Schizosaccharomyces pombe (Fission yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43792.53

構造登録者

Doamekpor, S.K.,Tong, L. (登録日: 2020-05-04, 公開日: 2020-05-20, 最終更新日: 2023-10-18)

• 主引用文献: Doamekpor, S.K.,Grudzien-Nogalska, E.,Mlynarska-Cieslak, A.,Kowalska, J.,Kiledjian, M.,Tong, L.; DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs.; Nucleic Acids Res., 48:6136-6148, 2020; PubMed: 32374864; DOI: 10.1093/nar/gkaa297

実験手法

X-RAY DIFFRACTION (1.9 Å)