6WUF

Crystal structure of mouse DXO in complex with 3'-FADP

Summary for 6WUF

Entry DOI	10.2210/pdb6wuf/pdb
Descriptor	Decapping and exoribonuclease protein, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name), 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	fad, 3'-fadp, rna, cap, decapping, hydrolase
Biological source	Mus musculus (Mouse)
Total number of polymer chains	1
Total formula weight	48391.22
Authors	Doamekpor, S.K.,Tong, L. (deposition date: 2020-05-04, release date: 2020-05-20, Last modification date: 2023-10-18)
Primary citation	Doamekpor, S.K.,Grudzien-Nogalska, E.,Mlynarska-Cieslak, A.,Kowalska, J.,Kiledjian, M.,Tong, L. DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs. Nucleic Acids Res., 48:6136-6148, 2020 Cited by PubMed: 32374864 DOI: 10.1093/nar/gkaa297 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation