6WTY

Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 253245

Summary for 6WTY

• Entry DOI: 10.2210/pdb6wty/pdb
• Related: 6WM9 6WN1 6WNO 6WOZ 6WQO 6WTU 6WTV
• Descriptor: reticulocyte binding protein 2b, 253245 Fab light chain, 253245 Fab heavy chain (3 entities in total)
• Functional Keywords: invasion, plasmodium vivax, malaria, antibody complex, cell invasion
• Biological source: Plasmodium vivax (strain Salvador I); More
• Total number of polymer chains: 12
• Total formula weight: 342638.24

Authors

Chan, L.J.,Dietrich, M.H.,Tham, W.H. (deposition date: 2020-05-04, release date: 2021-01-27, Last modification date: 2023-10-18)

• Primary citation: Chan, L.J.,Gandhirajan, A.,Carias, L.L.,Dietrich, M.H.,Vadas, O.,Visentin, R.,Franca, C.T.,Menant, S.,Soldati-Favre, D.,Mueller, I.,King, C.L.,Tham, W.H.; Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.; Nat Commun, 12:1538-1538, 2021; PubMed: 33750786; DOI: 10.1038/s41467-021-21811-2

Experimental method

X-RAY DIFFRACTION (3.481 Å)