6WT3
Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase
Summary for 6WT3
Entry DOI | 10.2210/pdb6wt3/pdb |
Related | 6WN4 |
Descriptor | 5D2 FAB HEAVY CHAIN, 5D2 FAB LIGHT CHAIN (3 entities in total) |
Functional Keywords | 5d2, lipoprotein lipase, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 2 |
Total formula weight | 47780.11 |
Authors | Luz, J.G.,Birrane, G.,Young, S.G.,Meiyappan, M.,Ploug, M. (deposition date: 2020-05-01, release date: 2020-07-29, Last modification date: 2023-10-18) |
Primary citation | Luz, J.G.,Beigneux, A.P.,Asamoto, D.K.,He, C.,Song, W.,Allan, C.M.,Morales, J.,Tu, Y.,Kwok, A.,Cottle, T.,Meiyappan, M.,Fong, L.G.,Kim, J.E.,Ploug, M.,Young, S.G.,Birrane, G. The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase. J.Lipid Res., 61:1347-1359, 2020 Cited by PubMed: 32690595DOI: 10.1194/jlr.RA120000993 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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