6WO2
Crystal Structure of the Grb2 SH2 Domain in Complex with a Tripeptide: Ac-pY-Ac6c-N-isohexyl
Summary for 6WO2
| Entry DOI | 10.2210/pdb6wo2/pdb |
| Related | 4P9V 6WM1 |
| Descriptor | Growth factor receptor-bound protein 2, ACE-PTR-02K-ASN-U67, CALCIUM ION, ... (6 entities in total) |
| Functional Keywords | grb2 sh2 ligand preorganization, peptide binding protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 28919.65 |
| Authors | Martin, S.F.,Clements, J.H. (deposition date: 2020-04-24, release date: 2020-09-02, Last modification date: 2023-11-15) |
| Primary citation | Cramer, D.L.,Cheng, B.,Tian, J.,Clements, J.H.,Wypych, R.M.,Martin, S.F. Some thermodynamic effects of varying nonpolar surfaces in protein-ligand interactions. Eur.J.Med.Chem., 208:112771-112771, 2020 Cited by PubMed: 32916312DOI: 10.1016/j.ejmech.2020.112771 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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