6WIE
Post-catalytic nicked complex of human Polymerase Mu on a complementary DNA double-strand break substrate
Summary for 6WIE
Entry DOI | 10.2210/pdb6wie/pdb |
Descriptor | DNA-directed DNA/RNA polymerase mu, PYROPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... (14 entities in total) |
Functional Keywords | family x polymerase, nonhomologous end-joining, dna double-strand break repair, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 46383.82 |
Authors | Kaminski, A.M.,Kunkel, T.A.,Pedersen, L.C.,Bebenek, K. (deposition date: 2020-04-09, release date: 2020-10-07, Last modification date: 2023-10-18) |
Primary citation | Kaminski, A.M.,Pryor, J.M.,Ramsden, D.A.,Kunkel, T.A.,Pedersen, L.C.,Bebenek, K. Structural snapshots of human DNA polymerase mu engaged on a DNA double-strand break. Nat Commun, 11:4784-4784, 2020 Cited by PubMed: 32963245DOI: 10.1038/s41467-020-18506-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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