6WH1

Structure of the complex of human DNA ligase III-alpha and XRCC1 BRCT domains

6WH1 の概要

• エントリーDOI: 10.2210/pdb6wh1/pdb
• 分子名称: X-ray repair cross complementing protein 1 variant, DNA ligase 3 alpha (3 entities in total)
• 機能のキーワード: dna ligase complex, dna repair, dna binding protein, dna binding protein-ligase complex, dna binding protein/ligase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 20383.17

構造登録者

Pourfarjam, Y.,Ellenberger, T.,Tainer, J.A.,Tomkinson, A.E.,Kim, I.K. (登録日: 2020-04-07, 公開日: 2020-12-02, 最終更新日: 2024-03-06)

• 主引用文献: Hammel, M.,Rashid, I.,Sverzhinsky, A.,Pourfarjam, Y.,Tsai, M.S.,Ellenberger, T.,Pascal, J.M.,Kim, I.K.,Tainer, J.A.,Tomkinson, A.E.; An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase III alpha within a flexible DNA repair complex.; Nucleic Acids Res., 49:306-321, 2021; PubMed: 33330937; DOI: 10.1093/nar/gkaa1188

実験手法

X-RAY DIFFRACTION (2.4 Å)