6WEO

IL-22 Signaling Complex with IL-22R1 and IL-10Rbeta

6WEO の概要

• エントリーDOI: 10.2210/pdb6weo/pdb
• 分子名称: Interleukin-10 receptor subunit beta, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-3)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
• 機能のキーワード: interleukin, receptor, cytokine, signaling
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 36
• 化学式量合計: 781898.09

構造登録者

Saxton, R.A.,Jude, K.M.,Henneberg, L.T.,Garcia, K.C. (登録日: 2020-04-02, 公開日: 2021-04-28, 最終更新日: 2023-10-18)

• 主引用文献: Saxton, R.A.,Henneberg, L.T.,Calafiore, M.,Su, L.,Jude, K.M.,Hanash, A.M.,Garcia, K.C.; The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design.; Immunity, 54:660-672.e9, 2021; PubMed: 33852830; DOI: 10.1016/j.immuni.2021.03.008

実験手法

X-RAY DIFFRACTION (2.6 Å)