6WAR

Crystal structure of the MERS-CoV RBD bound by the neutralizing single-domain antibody MERS VHH-55

6WAR の概要

• エントリーDOI: 10.2210/pdb6war/pdb
• 分子名称: Spike protein, nanobody MERS VHH-55, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: mers-cov, nanobody, coronavirus, rbd, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Middle East respiratory syndrome-related coronavirus (MERS-CoV); 詳細
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 312836.74

構造登録者

Wrapp, D.,Torres, G.M.,McLellan, J.S. (登録日: 2020-03-25, 公開日: 2020-04-08, 最終更新日: 2023-10-18)

• 主引用文献: Wrapp, D.,De Vlieger, D.,Corbett, K.S.,Torres, G.M.,Wang, N.,Van Breedam, W.,Roose, K.,van Schie, L.,Hoffmann, M.,Pohlmann, S.,Graham, B.S.,Callewaert, N.,Schepens, B.,Saelens, X.,McLellan, J.S.; Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.; Cell, 181:1004-, 2020; PubMed: 32375025; DOI: 10.1016/j.cell.2020.04.031

実験手法

X-RAY DIFFRACTION (3.4 Å)