6WAD

Crystal Structure of Human Protein arginine N-methyltransferase 6 (PRMT6) in complex with MT2739 inhibitor

6WAD の概要

• エントリーDOI: 10.2210/pdb6wad/pdb
• 分子名称: Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE, 5-bromo-N-(diphenylmethyl)-N-methylthiophene-2-carboxamide, ... (4 entities in total)
• 機能のキーワード: prmt6 and mt2739 inhibitor, structural genomics, structural genomics consortium, sgc, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42845.28

構造登録者

Halabelian, L.,Zeng, H.,Dong, A.,Schapira, M.,De Freitas, R.F.,Hutchinson, A.,Seitova, A.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Brown, P.J.,Structural Genomics Consortium (SGC) (登録日: 2020-03-25, 公開日: 2020-09-02, 最終更新日: 2023-10-18)

• 主引用文献: Halabelian, L.,Zeng, H.,Dong, A.,Schapira, M.,De Freitas, R.F.,Hutchinson, A.,Seitova, A.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Brown, P.J.,Structural Genomics Consortium (SGC); Crystal Structure of Human Protein arginine N-methyltransferase 6 (PRMT6) in complex with MT2739 inhibitor; to be published,

実験手法

X-RAY DIFFRACTION (2.45 Å)