6W7V
Structure of rabbit actin in complex with truncated analog of Mycalolide B
Summary for 6W7V
| Entry DOI | 10.2210/pdb6w7v/pdb |
| Related | 6MGO |
| Descriptor | Actin, alpha skeletal muscle, CALCIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (7 entities in total) |
| Functional Keywords | actin, toxin, complex, contractile protein |
| Biological source | Oryctolagus cuniculus (Rabbit) |
| Total number of polymer chains | 1 |
| Total formula weight | 43824.74 |
| Authors | Allingham, J.S.,Deng, X.,Trofimova, D. (deposition date: 2020-03-19, release date: 2020-10-21, Last modification date: 2023-10-18) |
| Primary citation | Pipaliya, B.V.,Trofimova, D.N.,Grange, R.L.,Aeluri, M.,Deng, X.,Shah, K.,Craig, A.W.,Allingham, J.S.,Evans, P.A. Truncated Actin-Targeting Macrolide Derivative Blocks Cancer Cell Motility and Invasion of Extracellular Matrix. J.Am.Chem.Soc., 143:6847-6854, 2021 Cited by PubMed: 33938740DOI: 10.1021/jacs.0c12404 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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