6W66
The structure of the F64A, S172A mutant Keap1-BTB domain in complex with SKP1-FBXL17
Summary for 6W66
| Entry DOI | 10.2210/pdb6w66/pdb |
| Descriptor | S-phase kinase-associated protein 1, F-box/LRR-repeat protein 17, Kelch-like ECH-associated protein 1 (3 entities in total) |
| Functional Keywords | e3 ligase, complex, btb domain, ligase, ligase-signaling protein complex, ligase/signaling protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 78511.14 |
| Authors | Mena, E.L.,Gee, C.L.,Kuriyan, J.,Rape, M. (deposition date: 2020-03-16, release date: 2020-08-19, Last modification date: 2023-10-18) |
| Primary citation | Mena, E.L.,Jevtic, P.,Greber, B.J.,Gee, C.L.,Lew, B.G.,Akopian, D.,Nogales, E.,Kuriyan, J.,Rape, M. Structural basis for dimerization quality control. Nature, 586:452-456, 2020 Cited by PubMed: 32814905DOI: 10.1038/s41586-020-2636-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.21 Å) |
Structure validation
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