6W2L
Crystal structure of human dehydrodolichyl diphosphate synthase (NgBR/DHDDS) in complex with Mg and IPP
Summary for 6W2L
Entry DOI | 10.2210/pdb6w2l/pdb |
Descriptor | Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Dehydrodolichyl diphosphate synthase complex subunit NUS1, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | cis-prenyltransferase, dehydrodolichyl diphosphate synthase, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 63058.15 |
Authors | Edani, B.H.,Ha, Y.,Sessa, W.C. (deposition date: 2020-03-06, release date: 2020-08-19, Last modification date: 2023-10-18) |
Primary citation | Edani, B.H.,Grabinska, K.A.,Zhang, R.,Park, E.J.,Siciliano, B.,Surmacz, L.,Ha, Y.,Sessa, W.C. Structural elucidation of thecis-prenyltransferase NgBR/DHDDS complex reveals insights in regulation of protein glycosylation. Proc.Natl.Acad.Sci.USA, 117:20794-20802, 2020 Cited by PubMed: 32817466DOI: 10.1073/pnas.2008381117 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.306 Å) |
Structure validation
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