6VZH

Structure of Human Vaccinia-related Kinase 1 (VRK1) Bound to LDSM311

6VZH の概要

• エントリーDOI: 10.2210/pdb6vzh/pdb
• 分子名称: Serine/threonine-protein kinase VRK1, SULFATE ION, (7~{R})-2-[[3,5-bis(fluoranyl)-4-oxidanyl-phenyl]amino]-5,7-dimethyl-8-prop-2-ynyl-7~{H}-pteridin-6-one, ... (5 entities in total)
• 機能のキーワード: protein kinase, inhibitor, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 166197.80

構造登録者

dos Reis, C.V.,Dutra, L.A.,Gama, F.,Ferreira, M.,Mascarello, A.,Azevedo, H.,Guimaraes, C.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Counago, R.M.,Structural Genomics Consortium (SGC) (登録日: 2020-02-28, 公開日: 2020-03-11, 最終更新日: 2023-10-11)

• 主引用文献: dos Reis, C.V.,Dutra, L.A.,Gama, F.,Ferreira, M.,Mascarello, A.,Azevedo, H.,Guimaraes, C.R.W.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Counago, R.M.; Structure of Human Vaccinia-related Kinase 1 (VRK1) Bound to LDSM311; To be Published,

実験手法

X-RAY DIFFRACTION (2.55 Å)