6VYJ
Human UHRF1 TTD domain in complex with a fragment
Summary for 6VYJ
Entry DOI | 10.2210/pdb6vyj/pdb |
Descriptor | E3 ubiquitin-protein ligase UHRF1, 2,4-dimethylpyridine, beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | ligase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 19606.76 |
Authors | Campbell, J.C.,Chang, L.,Young, D.W. (deposition date: 2020-02-26, release date: 2021-01-27, Last modification date: 2023-10-11) |
Primary citation | Chang, L.,Campbell, J.,Raji, I.O.,Guduru, S.K.R.,Kandel, P.,Nguyen, M.,Liu, S.,Tran, K.,Venugopal, N.K.,Taylor, B.C.,Holt, M.V.,Young, N.L.,Samuel, E.L.G.,Jain, P.,Santini, C.,Sankaran, B.,MacKenzie, K.R.,Young, D.W. Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery. Sci Rep, 11:1121-1121, 2021 Cited by PubMed: 33441849DOI: 10.1038/s41598-020-80588-4 PDB entries with the same primary citation |
Experimental method |
Structure validation
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