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6VY2

Cryo-EM structure of M1214_N1 Fab in complex with CH505 TF chimeric SOSIP.664 Env trimer

Summary for 6VY2
Entry DOI10.2210/pdb6vy2/pdb
EMDB information21456
DescriptorGlycoprotein 120, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
Functional Keywordscryo-em, broadly neutralizing antibody, bnab, fab, human immunodeficiency virus, hiv-1, ch505, sosip, env, immune system
Biological sourceHuman immunodeficiency virus 1
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Total number of polymer chains12
Total formula weight394729.68
Authors
Chan, K.-W.,Kong, X.P. (deposition date: 2020-02-25, release date: 2020-05-06, Last modification date: 2020-07-29)
Primary citationJia, M.,Liberatore, R.A.,Guo, Y.,Chan, K.W.,Pan, R.,Lu, H.,Waltari, E.,Mittler, E.,Chandran, K.,Finzi, A.,Kaufmann, D.E.,Seaman, M.S.,Ho, D.D.,Shapiro, L.,Sheng, Z.,Kong, X.P.,Bieniasz, P.D.,Wu, X.
VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA.
Cell Host Microbe, 27:963-, 2020
Cited by
PubMed: 32315598
DOI: 10.1016/j.chom.2020.03.024
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.86 Å)
Structure validation

217705

건을2024-03-27부터공개중

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