6VXY

Triazole bridged SFTI1 inhibitor in complex with beta-trypsin

Summary for 6VXY

• Entry DOI: 10.2210/pdb6vxy/pdb
• Related: 6U22 6U24
• Related PRD ID: PRD_002374
• Descriptor: Cationic trypsin, SFTI1 inhibitor GLY-ARG-GLY-THR-LYS-SER-ILE-PRO-PRO-ILE-ALA-PHE-PRO-ASP, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: triazole, peptidomimetic, biosynthetic protein
• Biological source: Bos taurus (Bovine); More
• Total number of polymer chains: 2
• Total formula weight: 24905.13

Authors

White, A.M.,King, G.J.,Durek, T.,Craik, D.J. (deposition date: 2020-02-25, release date: 2020-07-01, Last modification date: 2023-10-11)

• Primary citation: White, A.M.,de Veer, S.J.,Wu, G.,Harvey, P.J.,Yap, K.,King, G.J.,Swedberg, J.E.,Wang, C.K.,Law, R.H.P.,Durek, T.,Craik, D.J.; Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides.; Angew.Chem.Int.Ed.Engl., 2020; PubMed: 32270580; DOI: 10.1002/anie.202003435

Experimental method

X-RAY DIFFRACTION (1.398 Å)