6VXE

Crystal structure of hydroxyproline dehydratase (HypD) from Clostridioides difficile with substrate trans-4-hydroxy-L-proline bound

6VXE の概要

• エントリーDOI: 10.2210/pdb6vxe/pdb
• 分子名称: Trans-4-hydroxy-L-proline dehydratase, 4-HYDROXYPROLINE (3 entities in total)
• 機能のキーワード: glycyl radical enzyme, hydroxyproline dehydratase, lyase
• 由来する生物種: Clostridioides difficile 70-100-2010
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 732701.91

構造登録者

Backman, L.R.F.,Drennan, C.L. (登録日: 2020-02-21, 公開日: 2020-04-08, 最終更新日: 2023-10-11)

• 主引用文献: Backman, L.R.,Huang, Y.Y.,Andorfer, M.C.,Gold, B.,Raines, R.T.,Balskus, E.P.,Drennan, C.L.; Molecular basis for catabolism of the abundant metabolitetrans-4-hydroxy-L-proline by a microbial glycyl radical enzyme.; Elife, 9:-, 2020; PubMed: 32180548; DOI: 10.7554/eLife.51420

実験手法

X-RAY DIFFRACTION (2.464 Å)