6VTW
De novo protein design enables the precise induction of RSV-neutralizing antibodies
Summary for 6VTW
Entry DOI | 10.2210/pdb6vtw/pdb |
Descriptor | S4_2.45, 101F Fab Light Chain, 101F Fab Heavy Chain, ... (4 entities in total) |
Functional Keywords | de novo designed, immunogens, antibodies, in vivo, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 3 |
Total formula weight | 52477.77 |
Authors | Jardetzky, T.,Correia, B. (deposition date: 2020-02-13, release date: 2020-04-15, Last modification date: 2023-10-11) |
Primary citation | Sesterhenn, F.,Yang, C.,Bonet, J.,Cramer, J.T.,Wen, X.,Wang, Y.,Chiang, C.I.,Abriata, L.A.,Kucharska, I.,Castoro, G.,Vollers, S.S.,Galloux, M.,Dheilly, E.,Rosset, S.,Corthesy, P.,Georgeon, S.,Villard, M.,Richard, C.A.,Descamps, D.,Delgado, T.,Oricchio, E.,Rameix-Welti, M.A.,Mas, V.,Ervin, S.,Eleouet, J.F.,Riffault, S.,Bates, J.T.,Julien, J.P.,Li, Y.,Jardetzky, T.,Krey, T.,Correia, B.E. De novo protein design enables the precise induction of RSV-neutralizing antibodies. Science, 368:-, 2020 Cited by PubMed: 32409444DOI: 10.1126/science.aay5051 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report