6VRX
Mucor circinelloides FKBP12 protein bound with FK506 in P3221 space group
Summary for 6VRX
Entry DOI | 10.2210/pdb6vrx/pdb |
Related | 6VCT |
Descriptor | Peptidylprolyl isomerase, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN (3 entities in total) |
Functional Keywords | fk506-binding protein 1a, fkbp12, fk506, isomerase |
Biological source | Mucor circinelloides |
Total number of polymer chains | 4 |
Total formula weight | 51598.73 |
Authors | Gobeil, S.,Spicer, L. (deposition date: 2020-02-10, release date: 2020-12-16, Last modification date: 2023-10-11) |
Primary citation | Gobeil, S.M.,Bobay, B.G.,Juvvadi, P.R.,Cole, D.C.,Heitman, J.,Steinbach, W.J.,Venters, R.A.,Spicer, L.D. Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs. Mbio, 12:e0300021-e0300021, 2021 Cited by PubMed: 34809463DOI: 10.1128/mBio.03000-21 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.54 Å) |
Structure validation
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