6VPP

Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state

6VPP の概要

• エントリーDOI: 10.2210/pdb6vpp/pdb
• EMDBエントリー: 21314 21315
• 分子名称: Tubulin alpha-1A chain, Tubulin beta chain, Kinesin-like protein Klp61F, ... (6 entities in total)
• 機能のキーワード: kinesin-5, klp61f, microtubules, mitotic spindles, nucleotide-free state, cell cycle, motor protein
• 由来する生物種: Drosophila melanogaster (Fruit fly); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 143647.06

構造登録者

Bodrug, T.,Wilson-Kubalek, E.M.,Nithianantham, S.,Debs, G.,Sindelar, C.V.,Milligan, R.,Al-Bassam, J. (登録日: 2020-02-04, 公開日: 2020-02-19, 最終更新日: 2024-03-06)

• 主引用文献: Bodrug, T.,Wilson-Kubalek, E.M.,Nithianantham, S.,Thompson, A.F.,Alfieri, A.,Gaska, I.,Major, J.,Debs, G.,Inagaki, S.,Gutierrez, P.,Gheber, L.,McKenney, R.J.,Sindelar, C.V.,Milligan, R.,Stumpff, J.,Rosenfeld, S.S.,Forth, S.T.,Al-Bassam, J.; The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.; Elife, 9:-, 2020; PubMed: 31958056; DOI: 10.7554/eLife.51131

実験手法

ELECTRON MICROSCOPY (4.4 Å)