6VO4
Crystal Structure Analysis of BFL1
Summary for 6VO4
Entry DOI | 10.2210/pdb6vo4/pdb |
Descriptor | Bcl-2-related protein A1 (2 entities in total) |
Functional Keywords | bfl-1/a1, bcl-2 family, apoptosis, disulfide tethering, small molecule, inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 18596.06 |
Authors | Seo, H.-S.,Dhe-Paganon, S. (deposition date: 2020-01-29, release date: 2020-06-03, Last modification date: 2023-10-11) |
Primary citation | Harvey, E.P.,Hauseman, Z.J.,Cohen, D.T.,Rettenmaier, T.J.,Lee, S.,Huhn, A.J.,Wales, T.E.,Seo, H.S.,Luccarelli, J.,Newman, C.E.,Guerra, R.M.,Bird, G.H.,Dhe-Paganon, S.,Engen, J.R.,Wells, J.A.,Walensky, L.D. Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering. Cell Chem Biol, 27:647-, 2020 Cited by PubMed: 32413285DOI: 10.1016/j.chembiol.2020.04.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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