6VN7

Cryo-EM structure of an activated VIP1 receptor-G protein complex

Summary for 6VN7

• Entry DOI: 10.2210/pdb6vn7/pdb
• EMDB information: 21249
• Descriptor: Vasoactive intestinal polypeptide receptor 1, Pituitary adenylate cyclase-activating polypeptide, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... (8 entities in total)
• Functional Keywords: vasoactive intestinal polypeptide receptor, vip1r, g protein-coupled receptor, gs protein, cryo-em structure, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 182104.22

Authors

Duan, J.,Shen, D.-D.,Zhou, X.E.,Liu, Q.-F.,Zhuang, Y.-W.,Zhang, H.-B.,Xu, P.-Y.,Ma, S.-S.,He, X.-H.,Melcher, K.,Zhang, Y.,Xu, H.E.,Yi, J. (deposition date: 2020-01-29, release date: 2020-09-02)

• Primary citation: Duan, J.,Shen, D.D.,Zhou, X.E.,Bi, P.,Liu, Q.F.,Tan, Y.X.,Zhuang, Y.W.,Zhang, H.B.,Xu, P.Y.,Huang, S.J.,Ma, S.S.,He, X.H.,Melcher, K.,Zhang, Y.,Xu, H.E.,Jiang, Y.; Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy.; Nat Commun, 11:4121-4121, 2020; PubMed: 32807782; DOI: 10.1038/s41467-020-17933-8

Experimental method

ELECTRON MICROSCOPY (3.2 Å)