6VN1

A 2.8 Angstrom Cryo-EM Structure of a Glycoprotein B-Neutralizing Antibody Complex Reveals a Critical Domain for Herpesvirus Fusion Initiation

Summary for 6VN1

• Entry DOI: 10.2210/pdb6vn1/pdb
• EMDB information: 21247
• Descriptor: Human monoclonal antibody 93k variable light chain, Human monoclonal antibody 93k variable heavy chain, Envelope glycoprotein B (3 entities in total)
• Functional Keywords: varicella zoster virus, glycoprotein b, neutralization, monoclonal antibody, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 9
• Total formula weight: 392960.77

Authors

Oliver, S.L. (deposition date: 2020-01-29, release date: 2020-07-15, Last modification date: 2020-09-02)

• Primary citation: Oliver, S.L.,Xing, Y.,Chen, D.H.,Roh, S.H.,Pintilie, G.D.,Bushnell, D.A.,Sommer, M.H.,Yang, E.,Carfi, A.,Chiu, W.,Arvin, A.M.; A glycoprotein B-neutralizing antibody structure at 2.8 angstrom uncovers a critical domain for herpesvirus fusion initiation.; Nat Commun, 11:4141-4141, 2020; PubMed: 32811830; DOI: 10.1038/s41467-020-17911-0

Experimental method

ELECTRON MICROSCOPY (2.8 Å)