6VMK

Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12

Summary for 6VMK

• Entry DOI: 10.2210/pdb6vmk/pdb
• Descriptor: Complement factor D, Fab Y49R light chain, Fab Y49R heavy chain, ... (6 entities in total)
• Functional Keywords: cfd, factor d, fab, hydrolase, hydrolase-immune system complex, hydrolase/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 48
• Total formula weight: 1146018.37

Authors

Wu, P.,Harris, S.F.,Eigenbrot, C. (deposition date: 2020-01-28, release date: 2021-02-03, Last modification date: 2024-10-30)

• Primary citation: Dion, M.,Wu, P.,Morando, A.,Bullen, G.,Shatz, W.,Harris, S.F.,Eigenbrot, C.,Loyet, K.M.,Yadav, D.,Tassew, N.,Booler, H.,Scheer, J.,Kelley, R.F.,Tesar, D.B.; Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.01 Å)